HPE ProLiant DL380 Gen10 Server

Executive Summary

The HPE ProLiant DL380 Gen10 Server is a industry-leading 2U 2-socket rack server designed to deliver world-class performance, expandability, and security for multi-workload compute environments. Powered by Intel® Xeon® Scalable Processors, it supports flexible drive configurations, high-density DDR4 memory, and advanced management via HPE iLO 5.

Technical Specifications

Processor & Architecture

• Processor Family: 1st & 2nd Generation Intel® Xeon® Scalable Processors (Bronze 3100/3200, Silver 4100/4200, Gold 5100/5200/6100/6200, Platinum 8100/8200 series)

• Processor Sockets: 2 Sockets (LGA3647)

• Core Count: Up to 28 Cores per processor (Up to 56 cores total)

• Max Frequency: Up to 3.9 GHz base / 4.5 GHz Turbo

• Chipset: Intel® C621 Chipset

Memory & Persistent Storage

• Memory Slots: 24 DIMM slots (12 slots per processor, 6 channels per processor)

• Memory Type: HPE DDR4 SmartMemory (RDIMM, LRDIMM)

• Max Speed: Up to 2933 MT/s (dependent on CPU model)

• Max Capacity:

  • Up to 3.0 TB (24 x 128 GB LRDIMM)

  • Up to 6.0 TB with Intel® Optane™ Persistent Memory 100 Series for HPE (12 x 512 GB)

• Memory Protection: Advanced ECC, Memory Online Spare, Memory Mirroring

Storage Controllers & Drive Bays

• Primary Storage Controllers:

  • Software RAID: HPE Smart Array S100i (SATA only)

  • Performance RAID: HPE Smart Array P408i-a / P408i-p / P816i-a / P408e-p (12G SAS / 6G SATA)

  • Essential RAID: HPE Smart Array E208i-a / E208i-p / E208e-p

• Drive Bay Configurations:

  • 8 SFF (Small Form Factor) SAS/SATA, expandable to 24 SFF + 6 SFF rear drives

  • 12 LFF (Large Form Factor) SAS/SATA, expandable to 19 LFF (12 Front + 4 Mid + 3 Rear)

  • NVMe Support: Up to 20 NVMe PCIe SSD drive options

Expansion Slots & I/O

• PCIe Slots: Up to 8 PCIe 3.0 expansion slots (requires primary, secondary, and tertiary risers)

• Network Controller: Choice of HPE FlexibleLOM or PCIe standup network adapters (1GbE, 10GbE, 25GbE, 100GbE)

• USB Ports: Up to 5 USB 3.0 ports (1 front, 2 rear, 2 internal) + 1 MicroSD slot

• Video/Display: 1 Front VGA (optional), 1 Rear VGA, 1 DisplayPort (optional SFF chassis)

Power & Cooling

• Power Supply Units: HPE Flexible Slot (Flex Slot) Hot-Plug Power Supplies

  • 500W, 800W, or 1600W (80 PLUS Platinum / Titanium certification)

  • Redundancy: 1+1 Redundant power supply option

• System Fans: Hot-plug redundant fans (4 fans for single processor, 6 fans for dual processor / high power configurations)

Management & Security

• Infrastructure Management: HPE iLO 5 (Integrated Lights-Out) with Intelligent Provisioning, HPE OneView, and HPE iLO Amplifier Pack

• Silicon Root of Trust: Hardware-anchored security that validates firmware during startup

• Security Features: TPM 2.0 (Trusted Platform Module), Secure Boot, Chassis Intrusion Detection, AES & NSA Encryption Standards Compliance

Physical Dimensions & Weight

• Form Factor: 2U Rack Mountable

• Dimensions (H x W x D):

  • SFF Chassis: 8.74 x 44.55 x 67.94 cm (3.44 x 17.54 x 26.75 in)

  • LFF Chassis: 8.74 x 44.55 x 73.02 cm (3.44 x 17.54 x 28.75 in)

• Weight: 14.9 kg to 19.5 kg (32.8 lbs to 43.0 lbs) depending on drive configuration

Key Hardware Features

Feature Category	Capability / Specification	Key Benefit
Silicon Root of Trust	Immutable fingerprint burned into HPE iLO 5 ASIC	Prevents compromised code execution before OS boots
Intel Optane Persistent Memory	High-capacity, non-volatile memory modules	Speeds up in-memory databases and data analytics
FlexibleLOM & OCP 2.0	Modular networking interfaces without using PCIe slots	Saves general-purpose expansion slots for GPUs or NVMe accelerators
Tri-Mode Storage Controllers	Support for SAS, SATA, and NVMe drives on same controller	Simplifies storage architecture and expansion flexibility