Supermicro SuperServer SYS-621E-LTR
SYS-621E-LTR
Enterprise stock · tested · export documentation available
Product Overview: Supermicro SuperServer SYS-621E-LTR
The Supermicro SYS-621E-LTR is a high-density, dual-socket 2U rackmount enterprise server engineered for mainstream data center workloads, enterprise virtualization, cloud computing, storage expansion, and database management. Powered by 4th and 5th Generation Intel® Xeon® Scalable processors, it offers high memory bandwidth via DDR5, PCIe 5.0 expansion capabilities, and versatile hot-swap storage options.
Key Features & Highlights
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Processor Support: Dual Socket E (LGA-4677) supporting 4th and 5th Gen Intel® Xeon® Scalable Processors with TDP up to 350W per socket.
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Memory Architecture: 16x DDR5 DIMM slots supporting up to 4TB ECC Registered RDIMM modules with speeds up to 5600MHz.
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High-Speed I/O: Next-generation PCIe 5.0 slots delivering double the I/O throughput compared to PCIe 4.0.
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Flexible Storage: 12x 3.5″ hot-swap drive bays supporting SAS/SATA/NVMe configurations, plus onboard M.2 NVMe slots for OS boot drives.
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Network Versatility: Advanced I/O Module (AIOM) / OCP 3.0 networking slot allowing tailored networking configurations (1GbE, 10GbE, 25GbE, 100GbE).
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Power & Thermal: High-efficiency Redundant Titanium/Platinum level power supplies with optimized cooling subsystem.
Detailed Technical Specifications
| Feature / Category | Technical Specification |
| System Model | Supermicro SuperServer SYS-621E-LTR |
| Form Factor | 2U Rackmount |
| Motherboard | Supermicro X13DEI-T / Dual Socket Motherboard |
| Processor (CPU) |
Dual Socket E (LGA 4677) • Supports 4th & 5th Gen Intel® Xeon® Scalable Processors • Supports up to 350W TDP per CPU (Air Cooled) |
| Chipset | Intel® C741 Chipset |
| System Memory |
16x DIMM Slots (8 Channel per CPU) • Memory Type: DDR5 4800MHz / 5600MHz ECC RDIMM • Maximum Capacity: Up to 4TB ECC RDIMM |
| Drive Bays |
Front: 12x 3.5″ Hot-swap SAS/SATA/NVMe Drive Bays Internal / Boot: 2x PCIe 4.0 x4 M.2 NVMe (2280/22110) slots onboard |
| SAS/SATA Controller |
Onboard Intel® C741 SATA3 (6Gbps); RAID 0, 1, 5, 10 support. (Broadcom 12Gb/s SAS HW/SW RAID controller options via Add-on Cards) |
| Expansion Slots |
PCIe 5.0 Flexibility: • 4x PCIe 5.0 x16 Full-Height, Full-Length (FHFL) slots • 2x PCIe 5.0 x8 Full-Height, Half-Length (FHHL) slots • 1x PCIe 5.0 x8 AIOM / OCP 3.0 Mezzanine slot |
| Network Interface | Dual 10GbE RJ45 ports (Intel® X550) or flexible AIOM / OCP 3.0 mezzanine options |
| Management & Remote Control |
• IPMI 2.0 with dedicated LAN port • KVM over IP / Virtual Media • Supermicro Out-of-Band (OOB) / Redfish / SPM / SUM |
| Power Supply | Redundant 1200W / 1600W Titanium Level (96% Efficiency) Power Supplies |
| Cooling System | 4x High-performance 8cm PWM middle cooling fans with smart fan speed control |
| Dimensions (W × H × D) | 17.2 in (437 mm) × 3.5 in (88.9 mm) × 25.5 in (648 mm) |
| System Weight | Net Weight: ~36 lbs (16.3 kg) / Gross Weight: ~58 lbs (26.3 kg) |
Operating System & Virtualization Support
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Microsoft Windows Server: Windows Server 2019, Windows Server 2022
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Linux Distributions: Red Hat Enterprise Linux (RHEL) 8 / 9, SUSE Linux Enterprise Server (SLES) 15, Ubuntu Server 20.04 / 22.04 LTS
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Hypervisors / Cloud: VMware ESXi 7.0 / 8.0, Proxmox VE, Citrix Hypervisor, Microsoft Hyper-V

















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